Nobody ever said Borderlands 2 "tries to be a comedy". Including comedy elements/dialogue DOES NOT = trying to "be a comedy". If a speaker at an otherwise boring seminar, or a cancer survivor convention makes a couple jokes, that doesn't mean they are "trying to be a comedian". They are simply trying to lighten the mood a bit, and lessen the gravity of the situation. 2K/Gearbox is obviously (thankfully) not interested in copying the CODs of the gaming world, with a pseudo-realistic military shooter. That had a lot to do with their abrupt, and controversial change in art style, as well as the overall tone of the game. It's only natural, if you're trying to NOT take things...or be taken...too seriously, to inject some humor.
And, BTW, to compare...in any way...B2 to the typical Japanese crap that is Tokyo Jungle, is beyond stupid. ESPECIALLY when you do so in an attempt to prove that Borderlands 2 somehow failed at something that TJ was trying to achieve.....when it didn't.