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I have encouraged audiences to use Twitter with a specific hashtag during conference presentations. The demographic was similar to a college class of non-traditional aged students.
Several attendees tweeted comments and questions, which I could respond to immediately or at the end of the presentation. I think it's a good way to involve introverts who might not otherwise speak up. It also helps people who don't want to interrupt the flow, but who forget their questions before the Q&A. They can tweet questions as they think of them. You can use a computer, tablet or smartphone to monitor the hashtag's tweetstream. In quiet moments during class, you could join the online discussion, too.
The hashtag could also be used to communicate about class between sessions. Students could discuss homework. You could set up a search monitor their tweets to identify material they need more help with. If you chose, you could answer questions or clarify points as they arise.
2 years, 6 months ago on 6 Steps for Drafting a Social Media Policy